What Is Tretinoin? A Dermatologist-Favorite for Skin Renewal

Tretinoin is one of the most well-studied and dermatologist-recommended skincare ingredients for treating a wide range of skin concerns—from acne and fine lines to hyperpigmentation and uneven texture. But what exactly is it, and how does it work?

What Is Tretinoin?

Tretinoin is a prescription-strength topical retinoid derived from vitamin A. It’s also known by its brand names like Retin-A, Renova, and Altreno. Unlike over-the-counter retinol, tretinoin is more potent and works faster—making it a go-to solution for noticeable skin renewal.

How Does Tretinoin Work?

Tretinoin accelerates cell turnover, meaning it helps your skin shed dead cells and regenerate new ones more quickly. This process unclogs pores, boosts collagen production, and improves skin tone and texture over time.

Some of the key benefits include:

• Clearing and preventing acne
• Fading dark spots and hyperpigmentation
• Reducing fine lines and wrinkles
• Smoothing skin texture and minimizing pores
  

What Skin Concerns Does Tretinoin Treat?

Tretinoin is commonly prescribed for:

• Signs of aging: Tretinoin is clinically proven to reduce the appearance of fine lines, improve skin elasticity, and stimulate collagen.
• ‍Clear skin: It prevents new breakouts and clears existing ones by keeping pores clear.‍
• Hyperpigmentation: It helps fade dark spots, melasma, and sun damage over time.
  

How to Use Tretinoin Safely

Because it’s powerful, tretinoin can cause irritation when you first start using it. Here are a few tips:

• Start slow: Apply a pea-sized amount 2–3 times a week to build tolerance.
• Use at night: Tretinoin can make your skin more sensitive to sunlight.
• Moisturize: Always follow with a gentle, hydrating moisturizer.
• Be patient: It can take 8–12 weeks to see visible improvements.
  

Tretinoin vs. Retinol: What’s the Difference?

Both are vitamin A derivatives, but tretinoin is stronger and prescription-only. Retinol must be converted by the skin into retinoic acid before it becomes active, making it gentler—but also slower to work. Tretinoin delivers faster and more dramatic results but can be more irritating for beginners.

Is Tretinoin Right for You?

Tretinoin is a powerful tool for clearer, smoother, younger-looking skin—but it’s not for everyone. It’s best to consult a licensed provider to determine the right strength and frequency for your skin type and concerns.

Interested in trying tretinoin?

‍Alan Health offers custom formulations that combine tretinoin with other clinically proven ingredients like vitamin C—designed by dermatology experts and delivered to your door. Check out the Anti-Aging Complex here.