Maximizing your program: A guide to lifestyle changes with GLP-1 Medication

Dr. Rehan Umar
Alan Meds Medical Advisor
March 4, 2024
6 minutes

Embarking on a weight loss journey can be a transformative experience, especially with the assistance of medications like semaglutide or tirzepatide. This glucagon-like peptide-1 (GLP-1) receptor agonist has shown promise in supporting weight loss efforts. In this article, we will delve into practical strategies to maximize your weight loss results with semaglutide, emphasizing the importance of incorporating dietary and lifestyle changes for a holistic approach to well-being.

Follow a Balanced and Nutrient-Rich Diet

While there are a variety of dietary options, the general idea is to reduce your total energy (caloric) intake. 

  • Prioritize Whole Foods: Focus on incorporating whole, minimally processed foods into your diet. These include non-starchy fruits & vegetables, lean proteins, and whole grains. These nutrient-dense foods not only support weight loss but also provide essential vitamins and minerals for overall health.
  • Portion Control: Pay attention to portion sizes to avoid overeating. Use smaller plates, listen to your body's hunger and fullness cues, and savor each bite mindfully.
  • Elimination of all caloric beverages, which are often the source of unwanted calories, and processed foods
  • Avoiding calorie-dense foods with low satiety 

Stay Hydrated

  • Water is essential for overall health and plays a crucial role in weight loss. Aim to drink an adequate amount of water throughout the day, as it can help control appetite and promote proper digestion.

Incorporate Regular Physical Activity

  • Increasing energy expenditure through physical activity is a strong predictor of weight loss maintenance. 
  • Find Activities You Enjoy: Whether it's walking, cycling, dancing, or yoga, making exercise enjoyable increases the likelihood of consistency.
  • Gradual Progression: Start with activities suitable for your fitness level and gradually increase intensity. Consistency is key, so choose activities you can sustain over the long term.
  • Physical activity should be performed for ~30 minutes or more, 5-7 days a week, to prevent weight gain and to improve cardiovascular health 
  • Combined aerobic and resistance exercise is best for weight loss 

Prioritize Quality Sleep

  • Establish a Sleep Routine: Aim for 7-9 hours of quality sleep each night. Establishing a consistent sleep routine helps regulate hormones that influence appetite and metabolism, contributing to weight loss.

Mindful Eating Practices

  • Practice Mindful Eating: Be present and attentive while eating. Avoid distractions such as screens and savor each bite. This can help prevent overeating and foster a healthier relationship with food.

Additional Behavioral Changes

Your goal is to make long-term changes in eating habits by modifying and monitoring food intake and controlling cues that trigger eating 

  • Setting weight loss goals (ie. regular weighing) 
  • Setting behavioral goals (ie. make half of your plate fruits and vegetables, and eat fast food less than once a week)
  • Controlling or modifying the stimuli that activate eating
  • Eating style (ie. slowing down the eating process)
  • Behavioral contracting and reinforcement (ie. Reinforcing successful outcomes by providing rewards for weight loss may be beneficial) 
  • Meal planning (ie. Providing a defined meal structure results in greater weight loss than the absence of such a structure and use of portion-controlled plates or meal replacements) 
  • Cognitive restructuring or adopting positive rather than negative self-talk (ie. if one eats a piece of cake, choosing to exercise rather than blaming oneself)
  • Problem solving (ie. Developing strategies to manage food intake in difficult situations such as restaurants and parties) 

Track Your Progress

  • Keep a Journal: Track your meals, physical activity, and feelings associated with eating. This can provide valuable insights into your habits and help identify areas for improvement.
  • Celebrate Achievements: Acknowledge and celebrate your progress, whether it's reaching a weight loss milestone, establishing a new fitness routine, or adopting healthier eating habits.

Consult with Healthcare Professionals

  • Regular Check-ins: Maintain open communication with your healthcare provider throughout your weight loss journey. Regular check-ins allow for adjustments in your treatment plan and ensure your overall well-being.


Maximizing weight loss results with semaglutide involves a holistic approach that goes beyond medication. By incorporating balanced nutrition, regular physical activity, quality sleep, and mindful eating practices, you can enhance the effectiveness of semaglutide in achieving your weight loss goals. Remember, everyone's journey is unique, so tailor these strategies to your individual needs and work closely with your healthcare team for guidance and support. Embrace the positive changes in your lifestyle, and let them contribute to a healthier, happier you.

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