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Instructions:
Oral Acne Treatment

Storage

Store at room temperature (59°F to 86°F / 15°C to 30°C). Keep the bottle tightly closed and away from moisture, heat, and direct sunlight.

Instructions

This information is intended for individuals who have been prescribed Oral Spironolactone by their Alan Health provider.

Spironolactone is an oral prescription medication used to treat hormonal acne in women. It works by reducing the effects of certain hormones that contribute to oil production and acne breakouts. Your provider will determine the appropriate strength and titration schedule based on your needs.

How to Take Oral Spironolactone:

  • Take once daily, with or without food. Try to take it at the same time each day for best results.
  • Do not skip doses. Consistency is key—results build gradually over time.
  • Stay hydrated. Spironolactone is a mild diuretic, so drinking plenty of water can help prevent side effects.
  • Use effective birth control. This medication is not safe during pregnancy.
  • Continue your routine. You can use topical treatments like tretinoin or benzoyl peroxide alongside spironolactone, as directed by your provider.

Your provider will monitor your progress and adjust your plan if needed. Always follow their guidance and reach out with any questions.

Understanding your insulin syringe

Disclaimer: This information is for informational purposes only and not a substitute for medical advice. Your prescribed injection method and dosage are determined by your doctor and provided by your pharmacy. Always review the dosing instructions included with your medication and consult your doctor with any questions.

Measuring your dose

Insulin syringes are used for subcutaneous injections. They are marked in Units on the insulin syringe barrel (see illustration). Insulin syringes facilitate the precise measurement of tiny amounts of liquids which are ideal for medications such as insulin that require small and accurate dosing. Unit marks are also expressed in mL’s and can be interchangeably referenced. A prescriber may write a prescription in Units or in mL’s.

Within the amount of liquid is the prescribed mg dosage of your medication (see mg chart). Milligrams (mg) is not an amount of liquid, but rather the amount of drug that is within. The conversion between units and milligrams varies depending on the concentration of the product being used.


Example: 2.5 mg/ml = 2.5 mg of Oral Acne Treatment in every 1.0 ml or 100 Insulin Units.
Important safety information
Always refer to the prescription dosing instructions included with your medication.
Please read our full guide before taking any compounded medication. Read more

What can I expect?

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Safety information

The most common side effects are increased urination, dizziness, menstrual irregularities, breast tenderness, and mild stomach upset.

In rare cases, side effects include elevated potassium levels (which may cause weakness or heart palpitations), rash or allergic reaction, and severe fatigue or leg cramps. Seek immediate medical care if these occur. A full list of side effects can be found here.

Do not use this product if you are currently pregnant, breastfeeding, or plan to become pregnant or breastfeed without consulting a qualified healthcare provider.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Frequently Asked Questions

What is Oral Acne Treatment used for in skincare?

Oral Acne Treatment (Spironolactone) is a prescription oral medication primarily used to treat hormonal acne in women. It works by blocking androgens—hormones that can cause excess oil production and deep, cystic breakouts. Typically, your physician will start you on 50mg and, based on how you respond to the medication, titrate up to 100mg.

Who is Oral Acne Treatment best suited for?

It’s especially effective for adult women with hormonal acne, particularly those who experience breakouts along the jawline or chin, or who have flare-ups around their menstrual cycle or due to conditions like PCOS.

How long will it take to see results from Oral Acne Treatment for acne?

Most users begin noticing improvements between 8–12 weeks of daily use, with full results often seen after 4–6 months. Because spironolactone works gradually, consistency is key. Visit our Resource Center for more information on what to expect over time with oral spironolactone. 

Will my acne get worse before it gets better?

Some people experience a brief “purging” phase during the first few weeks, where breakouts may temporarily increase as pores begin to clear. This typically resolves as the treatment starts working.

What are the potential side effects?

Common side effects may include increased urination, breast tenderness, or changes in menstrual cycles. Serious side effects are rare but should be reported to your provider right away.

Is Oral Acne Treatment safe for long-term use?

Yes. With appropriate monitoring by your provider, spironolactone can be used safely over the long term to manage hormonal acne.

Can I take Oral Acne Treatment with topical acne treatments?

Yes. Many patients combine spironolactone with topicals like tretinoin or benzoyl peroxide for enhanced results. Your provider can recommend the best regimen for your skin type.

What happens if I stop taking Oral Acne Treatment?

If you stop treatment, your hormonal acne may return over time. Always speak with your provider before making any changes to your medication plan.

Why is spironolactone typically prescribed only for women?

Spironolactone treats acne and hair concerns by blocking androgens. In men, this can lead to side effects like breast tenderness or lower testosterone, so it’s generally prescribed only for women.

Can I take Oral Acne Treatment if I’m pregnant or trying to conceive?

Spironolactone is not recommended during pregnancy or while trying to conceive. Be sure to inform your provider if you’re planning for pregnancy or not using contraception.

What if I miss a dose?

If you miss a dose, skip the missed dose and continue with your regular schedule. Do not double up to make up for a missed dose.

Additional support

For details about your medication and dosing, please log in to your patient portal. Your physician is here to help with any medical questions. If you are experiencing a medical emergency, call 911 right away.

Standard Titration Schedule
Week 1-2
0.6 mg
15 mg/mL
Once Daily
Week 3-4
1.2 mg
15 mg/mL
Once Daily
Week 5-6
1.8 mg
15 mg/mL
Once Daily
Week 7-8
2.4 mg
15 mg/mL
Once Daily
Week 9+
3 mg
15 mg/mL
Once Daily
Standard Titration Schedule
Week 1-2
0.1 mg
100 mg/mL
2 times per week
Week 3-4
0.3 mg
100 mg/mL
2 times per week
Week 5+
0.5 mg
100 mg/mL
2 times per week
Metformin
Week 1-6
Getting Started
Mild nausea or digestive changes are common. Take with food to ease symptoms.
Week 7-12
Blood Sugar Begins to Stabilize
Side effects usually fade. You may notice steadier energy and reduced appetite.
Week 12+
Ongoing Metabolic Support
Blood sugar levels improve, and many users see benefits in A1C and weight over time.
Week 1-2
Getting Started
Mild nausea or digestive changes are common. Take with food to ease symptoms.
Week 3-6
Blood Sugar Begins to Stabilize
Side effects usually fade. You may notice steadier energy and reduced appetite.
Week 7-12
Ongoing Metabolic Support
Blood sugar levels improve, and many users see benefits in A1C and weight over time.
Anti-Aging Complex
Week 1-2
Initial Sensitivity & Purging
You may experience mild redness, dryness, or flaking. This is common as your skin acclimates to increased cell turnover.
Week 3-6
Smoother Skin, Less Pigmentation
Skin starts to feel smoother, breakouts may reduce, and early hyperpigmentation begins to fade. Hydration improves as hyaluronic acid builds the barrier.
Week 7-12
Firmer, Brighter, Even-Toned Skin
Fine lines soften, texture improves, and skin tone looks more even and youthful. Most users see continued improvement over 8–12 weeks.
Anti-Aging Serum
Week 1-4
Scalp Adjustment & Shedding
Some users experience temporary shedding as older hairs make way for new ones. The scalp may feel drier or mildly irritated—this typically resolves.
Week 5-8
Less Shedding, Healthier Scalp
Inflammation and dandruff may improve thanks to ketoconazole, while minoxidil starts stimulating follicle activity.
Week 9-16
Thicker, Fuller Hair
Hair density begins to visibly improve. Clinical use shows noticeable regrowth and stronger strands with consistent application over 2–4 months.
NAD+ Face Cream
Week 1-2
Instant Glow, Gentle Start
Some users report a visible glow or smoother texture within the first few applications. You may feel a light tingle—this is normal.
Week 3-6
Hydration, Tone, and Texture Improve
Skin often becomes more even-toned and hydrated, with reduced dullness and fine lines as cellular energy and barrier strength are restored.
Week 7-12
Firmer, Healthier-Looking Skin
Elasticity improves and wrinkles soften. Continued use supports deeper repair, giving skin a firmer, more resilient appearance with lasting radiance.
Generic Latisse
Week 1-4
Subtle Beginnings
You may not notice much change at first. This phase is about setting the foundation—bimatoprost is extending your lashes’ growth cycle behind the scenes.
Week 5-8
Early Lash Gains
Many users start seeing longer lashes and less lash shedding. Look for subtle darkening and early thickening along the lash line.
Week 9-16
Fuller, Longer, Darker Lashes
Expect dramatically enhanced lash length, volume, and color. Clinical studies show up to 106% improvement in fullness, 25% longer lashes, and 18% darker pigmentation by week 16. Continue using generic latisse to maintain results.
Rosacea Treatment
Week 1-2
Gentle Start, Possible Tingling
Skin may tingle or feel slightly dry as the formula gets to work. This is normal and usually fades quickly.
Week 3-4
Redness and Bumps Decrease
You may notice a reduction in inflammation, fewer breakouts, and a calmer appearance—especially around the cheeks and nose.
Week 5-8
Skin Tone Looks More Even
Most users see fewer flare-ups and smoother texture by week 6. Ongoing use helps maintain long-term skin balance.
Oral Acne Treatment
Week 1-2
Hormonal Reset Begins
Your oil production begins to regulate, but breakouts may temporarily persist. Some users experience a short purging phase.
Week 3-6
Fewer, Milder Breakouts
Acne lesions often appear less inflamed and less frequent, especially along the chin and jawline. Oiliness typically decreases.
Week 7-12
Clearer, More Balanced Skin
Many users see significant improvements by month 3—fewer cystic breakouts, smoother skin, and more even tone.
Oral Minoxidil
Week 1-4
Early Shedding is Normal
Some users experience an increase in shedding during the first month—this means older hairs are making way for new growth.
Week 5-12
Subtle Signs of Progress
You may notice reduced shedding or fine baby hairs emerging along the hairline or crown. Results are still building—stick with daily use.
Week 12+
Noticeable Regrowth and Density
Hair appears fuller and thicker in areas of previous thinning. Most users see visible improvements in density and coverage by month 6 with consistent use.
Acne Cream
Week 1-2
Skin Adjustment Phase
Mild dryness, peeling, or a temporary purge may occur as your skin adjusts to increased cell turnover. Use moisturizer and SPF daily.
Week 3-6
Breakouts Diminish, Texture Improves
Blemishes begin to clear, and skin feels smoother as clogged pores are cleared and inflammation subsides.
Week 7-12
Brighter, Healthier-Looking Skin
Expect fewer breakouts and a visible reduction in post-acne marks and roughness. Continued use supports long-term clarity.
The Spot Corrector
Week 1-2
Early Adjustment
Mild tingling or dryness is normal as your skin adjusts. Continue with once-daily use unless otherwise advised.
Week 3-8
Visible Improvement
Dark spots begin to fade and skin tone appears more even and calm.
Week 9-16
Full Results
Brighter, clearer skin with reduced discoloration and improved tone. Continued use is key to maintaining results.
Hair Regrowth Spray
Week 1-4
Adjustment Phase
Your scalp may feel dry or irritated as it adjusts. Initial shedding can occur as dormant follicles transition to active growth.
Week 5-12
Less Shedding, Early Hints of Growth
You may see less hair in your brush and some fine regrowth beginning. Tretinoin and melatonin support absorption and scalp health.
Week 12+
Fuller Hair, Visible Improvements
With daily use, most users notice increased hair density and coverage in thinning areas. Continued use beyond month 3 is essential to maintain and build on results.