
Low Dose Naltrexone
Boosts immunity & reduces inflammation
No insurance required
Prescribed 100% online
Expedited Shipping

How does Low Dose Naltrexone work?

Taken daily, it gently supports immune regulation, eases chronic inflammation, and may improve mood, energy, sleep, and overall resilience over time.
Key benefits
Why choose Low Dose Naltrexone?
Calms Chronic Inflammation
Helps ease low-grade, persistent inflammation that may contribute to fatigue, discomfort, and immune-related symptoms.
Balances Immune Function
Supports a regulated immune response—ideal for those managing autoimmune conditions or looking to strengthen overall resilience.
Enhances Mood, Sleep & Clarity
May boost natural endorphins to improve emotional well-being, sleep quality, and focus.
Gentle and Well-Tolerated
As a low-dose therapy, LDN is well-tolerated and often used as part of a long-term wellness routine.


3 easy steps to get started
Get started with a 3-minute quiz
Answer a few questions to see if you qualify—100% online.
Virtual consultation
Chat with a US-certified doctor to get your prescription.
Expedited Shipping
Your medication will ship from a US-accredited pharmacy partner right to your doorstep—that’s right, no backorder.
Feel your best with a plan built just for you
Backed by our doctors & specialist teams
Holistic care
We support your journey with expert guidance and resources to help you achieve optimal results, including fitness programs, dietitian-designed meal plans, and practical lifestyle tips.
Made in the USA
We only work with accredited pharmacies that adhere to rigorous quality standards.
U.S. based support
Our U.S. based doctors and care team are available to help you every step of the way, with unlimited access.

Backed by Board-Certified Doctors
Trusted for over 100K treatments

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Frequently Asked Questions
Low-Dose Naltrexone (LDN) is a well-tolerated medication that may support the immune system, reduce chronic inflammation, and improve mood and energy levels. Originally used at higher doses to treat addiction, at low doses it works very differently—by helping the body rebalance its immune response and increase natural endorphin production.
At low doses, naltrexone briefly blocks opioid receptors, prompting the body to produce more natural endorphins. These endorphins help calm the immune system and reduce chronic inflammation.
LDN is generally well-tolerated. Some people may experience vivid dreams, trouble sleeping, headaches, or mild digestive issues when starting. These effects typically fade as your body adjusts.
You may start to feel subtle improvements—like better sleep, mood, or less discomfort—within a few weeks. Full benefits often build over several months of consistent use.
Yes. Even at low doses, naltrexone is a prescription-only medication and must be prescribed by a licensed provider.
LDN may interact with opioid-based medications and should not be used at the same time. Always consult your prescribing provider to review potential interactions with your current treatments.
Many people take LDN for months or even years as part of their ongoing wellness plan. It’s considered a low-risk option for long-term use under medical supervision.