Acne Cream
Clears active acne fast: Combines tretinoin and clindamycin to fight bacteria and unclog pores.
No insurance required
Expedited shipping, prescribed 100% online

How does Acne Cream work?

This dermatologist-formulated cream combines two clinically proven ingredients that work together to treat and prevent acne.
It targets both comedonal acne (like blackheads and whiteheads) and inflammatory acne (red, swollen pimples). Tretinoin enhances clindamycin’s absorption, making the combination more effective than either ingredient alone.
The result: a synergistic, nightly treatment that clears active breakouts, supports long-term skin health, and helps improve tone and texture over time.
Adults with mild to moderate acne, including blackheads, whiteheads, or inflamed pimples
Anyone looking to treat breakouts and prevent new ones with a single nightly cream
People dealing with post-acne marks, dark spots, or uneven texture
Learn more about how our Acne Cream works at the Alan Health Resource Center.
Why try Acne Cream?
Fast, Visible Results
Studies show improvements in as little as 4–8 weeks. This prescription-strength cream works quickly to reduce redness, clear breakouts, and smooth skin when used consistently.
Dual-Action Formula That Works
Combines tretinoin and clindamycin to treat both clogged pores and inflamed pimples—making it effective for most common types of acne.
Smoothes Skin, Even After Breakouts
Supports collagen production to improve texture and fade post-acne marks, so your skin looks clearer, not just breakout-free.


3 easy steps to get started
Get started with a 3-minute quiz
Answer a few questions about your health history, goals, and lifestyle—100% online.
Virtual consultation
Chat with a US-certified doctor to get your prescription.
Expedited Shipping
Your medication will ship from a US-accredited pharmacy partner right to your doorstep—that’s right, no backorder.
Made of highly-effective ingredients
Azelaic Acid
Reduces melanin production, calms inflammation, and helps with acne.
Azelaic Acid
Reduces melanin production, calms inflammation, and helps with acne.
Tranexamic Acid
Helps prevent pigmentation from hormonal and sun-related triggers.
Azelaic Acid
Reduces melanin production, calms inflammation, and helps with acne.
Tranexamic Acid
Helps prevent pigmentation from hormonal and sun-related triggers.
Niacinamide
Strengthens the skin barrier, reduces redness, and boosts overall brightness.
Azelaic Acid
Reduces melanin production, calms inflammation, and helps with acne.
Tranexamic Acid
Helps prevent pigmentation from hormonal and sun-related triggers.
Niacinamide
Strengthens the skin barrier, reduces redness, and boosts overall brightness.
Ingredient Name 4
Ingredient Body 4
Backed by our
doctors & specialist teams
Holistic care
We support your journey with expert guidance and resources to help you achieve optimal results, including fitness programs, dietitian-designed meal plans, and practical lifestyle tips.
Made in the USA
We only work with accredited pharmacies that adhere to rigorous quality standards.
U.S. based support
Our U.S. based doctors and care team are available to help you every step of the way, with unlimited access.


Backed by Board-Certified Doctors
“I love prescribing this combination for my acne patients because it tackles breakouts from two critical angles: tretinoin promotes skin cell turnover and unclogs pores, while clindamycin targets the bacteria driving inflammation. Together, they help reduce both active lesions and future breakouts, all while improving skin texture and preventing post-acne scars."
Trusted for over 100K treatments

Skin & Hair Programs
Tailored for You
Alan Health isn’t just a bandaid. We offer a holistic plan to support your well-being with prescription medication, lifestyle content, and a nutrition plan tailored to your unique needs. Plus, get expert support to guide you in your journey—all for one monthly price.
Frequently Asked Questions
Most people begin noticing visible improvements between 8 and 12 weeks. Early on, your skin may feel drier or experience mild purging as it adjusts. With consistent use, you can expect fewer breakouts, smoother texture, and reduced redness over time.
Learn more about how our Acne Cream works, and what to expect, here.
Yes—tretinoin increases sun sensitivity. Use daily sunscreen (SPF 30+), wear protective clothing, and limit sun exposure, especially during the first few weeks.
Yes—wait 20–30 minutes after applying the acne cream so it fully absorbs before applying moisturizer or makeup.
No. Tretinoin is contraindicated during pregnancy and nursing—always check with your provider before use.
Start with every-other-night use and add a basic moisturizer. Use gentle cleansers and avoid other strong actives until your skin adjusts.
Yes—tretinoin helps fade post-acne hyperpigmentation and smooth uneven texture by boosting skin renewal and collagen production.
It's best to avoid combining this cream with other strong actives like benzoyl peroxide, AHAs, or exfoliants, especially in the first few weeks. Stick to a gentle cleanser and moisturizer unless your provider advises otherwise.